Earliest Signs of Alzheimer’s

"We need to find and treat people much earlier."

With grim prognoses and very limited treatments for Alzheimer’s disease, early detection isn’t particularly advantageous. But that may be changing—fast. One of the hottest areas of Alzheimer's research involves treating people in the very earliest stages of the disease with drugs that decrease the production of amyloid beta (proteins that bunch together to form damaging plaques in the brain). Experts believe that people begin to develop amyloid plaques in their brains at least 10 years before they develop any obvious symptoms of dementia.

Reisa Sperling, MD, director of the Center for Alzheimer Research and Treatment at Brigham and Women’s Hospital in Boston is leading a new clinical trial, called theA4 study, which will evaluate patients with evidence of Alzheimer’s damage in the brain but who still have normal thinking and memory function. The trial will randomly assign groups to receive medication, and researchers will determine over three years whether the drugs affected the patients’ memory or levels of amyloid. “When a person already has a lot of memory trouble, they already have significant neuron loss,” says Dr. Sperling. “We need to find and treat people much earlier.” Here's what to watch for.

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What’s Behind These Doors

The house was built on a triangular lot. It was an affordable land space, but it was difficult to build upon.

I’ve seen some truly remarkable pieces of architecture while writing for LittleThings — especially tiny houses. Followers of the Tiny House Movement will be quick to tell you that a small space doesn’t mean a lack of options and possibilities. In fact, some tiny houses can be more impressive than huge mansions. I’ve seen tiny houses in the shape of crosses, boulders, piles of logs, and even Hobbit holes.

Recently, I saw photos of a gorgeous tiny house built in a triangle shape so it fits on a peculiarly shaped lot.

This Japanese house designed by the brilliant architects at Mizuishi Architects Atelier fits a family of three in a 594-square-foot home on an abnormally shaped property.

According to a study reported by the Guardian, quirky homes like these are more common in Japan because homeowners and architects can afford to build homes that may fade out of style. Homes are built more for style than longevity because of the frequency of earthquakes. Building codes get updated nearly every ten years and, as it stands right now, it is actually cheaper for many families to rebuild than to restructure. Most homes in Japan depreciate in value rapidly, and to make their home investments worth it, Japanese homeowners will destroy their house and build a brand new one to gain profit. This calls for a huge demand for more modern and innovative homes.

This planned obsolescence has made resulted in an increased demand for Japanese architects. There are 2.5 architects per 1,000 residents in Japan, while the United States has only .33 architects per every 1,000 residents.

The architects at Mizuishi Architects Atelier have done an incredible job making a deceptively amazing tiny house!

Of course, adding three levels of windows allows for lots of light to make the space feel a little larger.

But can such a narrow space really be nice to live in?

The answer is a resounding "Yes!"

The lofted area of the "steeple" provides a great children's playroom, but it can also be used as an office or spare bedroom.

The loft-style vaulted ceilings make it feel much airier and more spacious.

The ground floor is divided into a bedroom, living area, and kitchen.

This house has the beds out in the open in a studio format so that additional walls don't make it feel more closed off.

However, curtains around the bedroom area allow for some privacy.

There's even plenty of kitchen space.

Modern amenities and a sleek design help prevent this house from feeling cluttered.

With its river views, this house might be one of the most enviable new Japanese properties.

Personality Trait for Strawberry Ice-cream lovers

Strawberry lovers are introverts.

In a study by Hirsch for Baskin Robbins, strawberry lovers were often tolerant, devoted, and introverted; in research conducted for Dreyer's/Edy's, he found fans of the berry flavor were also logical and thoughtful.